|
|
EN

  • 業務谘詢

    中國：

    Email: marketing@yakkaa.com

    業務谘詢專線：400-780-8018

    （僅限服務谘詢，其他事宜請撥打川沙總部電話）

    川沙總部電話: +86 (21) 5859-1500

    海外：

    +1(626)986-9880(U.S. - West Coast)

    0044 7790 816 954 (Europe)

    Email:marketing@medicilon.com

在線留言×
點擊切換
Customer Center
客戶中心

H11-HLE是一種工具分子，可用於研究Fc在介導免疫檢查點治療中的作用，具有抗腫瘤功效

2023-06-28
|
訪問量：

4-H11-HLE-1.jpg

Immune checkpoint inhibition therapies have been used for multiple cancer research. H11-HLE is a tool molecule that allows the interrogation of the contribution of Fc in mediating immune checkpoint therapy. Half-life extended H11 (H11-HLE) induces potent anti-tumor efficacy in mouse syngeneic tumor models.

s gratefully acknowledge performing in vivo studies by Medicilon Preclinical Research LLC who performed the in vivo experiments.

Reference

Yosuke Sato, et al. Fc-independent functions of anti-CTLA-4 antibodies contribute to anti-tumor efficacy. Cancer Immunol Immunother. 2022 Oct;71(10):2421-2431. doi: 10.1007/s00262-022-03170-z.

相關新聞